Written by: THE BALANCE
Medically reviewed by Dr. Sarah Boss, MD
Last updated: January 19, 2026
Fact checked
Quick Summary
  • It is thought to stem from prolonged stress and exhaustion of adrenal glands that produce hormones such as cortisol and adrenaline.
  • These glands are involved in stress regulation and the general well-being of an individual.
  • When they get overwhelmed, they develop symptoms that affect daily function differently.

Adrenal fatigue is a condition that concerns women in particular. It is thought to stem from prolonged stress and exhaustion of adrenal glands that produce hormones such as cortisol and adrenaline. These glands are involved in stress regulation and the general well-being of an individual. When they get overwhelmed, they develop symptoms that affect daily function differently.

Females can experience adrenal gland issues differently, owing to the disturbance in the hormonal background, energy, mood, and menstrual cycle. It is necessary to understand these signs because it can be helpful in the early diagnosis of the condition. This article will discuss the symptoms of adrenal gland disorders in women, the concept of adrenal exhaustion, its causes, symptoms, and ways of dealing with it.

Adrenal fatigue is a term used to refer to a group of symptoms that are rather vague and include body pains, fatigue, anxiety, sleep disorders, and gastrointestinal disturbances [1]. It is believed to happen when the adrenal glands cannot produce enough hormones to cope with stress.

Role of Adrenal Glands

The adrenal glands are small triangular-shaped glands located on the upper part of the kidneys. They secrete hormones such as cortisol, adrenaline, and aldosterone which play a role in metabolism, immune response, blood pressure, and the body’s reaction to stress [1].

Difference from Other Adrenal Disorders

While Addison’s disease is a disease that is well understood and is characterized by the adrenal gland’s inability to produce adequate hormones, adrenal fatigue is not a disease that is recognized by mainstream medical practitioners. Addison’s disease is a condition that entails a partial or almost complete loss of adrenal gland function while adrenal fatigue refers to a partial adrenal gland dysfunction as a result of chronic stress.

Adrenal fatigue is believed to be on a continuum where the adrenal glands are not necessarily dysfunctional but rather are simply taxed and unable to function at their best. Although there is still controversy about the existence of adrenal fatigue among scientists, many people complain of symptoms associated with this condition, especially those who have to cope with constant stress, improper diet, and other difficulties in everyday life.

Some of the causes of adrenal fatigue in women include the following;

There are several causes of adrenal fatigue and they are more common in females than males. Knowledge of these causes can be useful in prevention as well as in the management of the disorder.

Chronic Stress and Its Impact: Cortisol is the ‘stress hormone’ and the adrenal glands are the organs that produce cortisol, when a person is constantly stressed either emotionally, physically, or even mentally the adrenals are overworked producing more cortisol to deal with the pressure [1]. This, over some time, leads to adrenal fatigue. Stress can be chronic or acute and it can originate from work-related stress, marital issues, financial concerns, or long-term health conditions.

Hormonal Imbalances: Hormonal changes are common in women at some stage in their lives such as during puberty, during the menstrual cycle, during pregnancy, and menopause. Some other factors such as thyroid or menopausal can exert even more pressure on the adrenal glands because the body is attempting to balance other hormones. For instance, during the menopausal period, the adrenals assume a more critical responsibility for hormone synthesis which can put a lot of pressure on them if they are already stressed.

Poor Diet and Lifestyle Factors: Caffeinated products, high-sugar products, and processed foods are some of the things that put pressure on the adrenal glands. Lack of sleep and physical over-exertion aggravates the problem. Unhealthy eating habits result in fluctuations in blood sugar levels, and this makes the adrenal glands release cortisol to balance blood sugar levels. Also, having too much caffeine can cause the adrenals to become stimulated and this can lead to a cycle of high energy and low energy that is tiring on the glands.

Environmental Toxins and Chronic Infections: Environmental pollutants including heavy metals and chemicals put pressure on the body’s detoxification organs including the adrenal glands. Any form of chronic infection whether viral or bacterial will also lead to a continuous stress response in the body which will drain the adrenal glands.

There are numerous symptoms and signs associated with adrenal fatigue and many of them may cause a considerable decline in a woman’s quality of life.

General Fatigue and Low Energy Levels

Fatigue is perhaps one of the most noticeable signs of adrenal fatigue; this is mostly because an individual suffering from adrenal fatigue will always feel tired even after a sound sleep at night [2]. Fatigue is a state of chronic exhaustion, and women with adrenal fatigue say they feel “spent” or “exhausted.”

Difficulty Waking Up in the Morning

Most women with adrenal fatigue have a hard time waking up in the morning even when they retire to bed early at night. This is because cortisol production is interrupted and its production is supposed to increase in the morning to make one alert.

Increased Cravings for Salty or Sugary Foods

Mineral imbalances such as low sodium and high potassium levels are some of the effects of adrenal fatigue resulting in a craving for salty foods. Also, low cortisol levels result in fluctuations in blood sugar levels which results in the need to take foods rich in sugar to increase energy.

Unexplained Weight Gain

Cortisol is also involved in the process of fat deposition, especially in the abdominal region. Adrenal fatigue in women makes the body retain fat as a form of self-protection from what the body perceives as danger.

Brain Fog and Difficulty Concentrating

Adrenal fatigue in women leads to a decline in brain function where one is overwhelmed when performing tasks that were easy to accomplish before, has poor concentration, and has poor memory, which can be described as “brain fog.

Difficulty Handling Stress 

In adrenal fatigue, the adrenal glands are unable to secrete the necessary stress hormones to deal with each day’s demands. This can lead to such symptoms as feeling easily stressed or being incapable of handling some situations that were previously easy to handle.

Weakened Immune System and Frequent Illness

Cortisol also has an influence on the immune system as well as on the regulation of inflammation. This is because, when cortisol levels are out of balance for a long time, the immune system is affected and women can easily fall sick or get infected by diseases such as colds and flu.

Adrenal fatigue can impact the emotional and mental health of a woman and can mimic or cause other mental disorders.

Link Between Adrenal Fatigue and Anxiety or Depression

Stress and adrenal disorders can cause imbalances in neurotransmitters, which are important for the regulation of mood such as serotonin and dopamine [2]. Some of the symptoms that women with adrenal fatigue may exhibit include; sadness, anxiety, or even depression. They might also feel a lack of feeling or emotional unresponsiveness.

Difficulty Coping with Everyday Stress

The common complaints of women with adrenal fatigue include the feeling of being easily overwhelmed when handling tasks, which were earlier handled without much difficulty. It might be difficult to accomplish even basic things and there might be hopelessness or an inability to find a way out of a problem.

Feelings of Overwhelm or Helplessness

Since women are always stressed and tired, they may develop feelings of hopelessness. The physical signs of adrenal fatigue coupled with the stress that the emotions bring, make them feel like they are fighting their bodies.

Reduced Motivation and Productivity

One of the effects of adrenal fatigue is that it reduces the desire to do the most basic tasks. Women may have problems with concentration, and this will lead to low productivity in their workplace or on the projects they are working on. This can result in frustration and poor mental health as people struggle to get what they want or need.

Identifying adrenal fatigue may be difficult, as it is not well understood in mainstream medicine. Nevertheless, there are ways of testing adrenals and, therefore, diagnosing related issues.

Why It’s Often Underdiagnosed in Conventional Medicine

The manifestations of adrenal fatigue are quite vague and may include fatigue, mood swings, poor digestion, and so on, which may be indicative of other diseases such as depression, thyroid disorders, or chronic fatigue syndrome. This is because adrenal fatigue is not a diagnosable disease, making many healthcare providers dismiss it, explaining the symptoms as being due to other factors or stress without researching further.

Tests Used to Detect Adrenal Gland Problems

Saliva Cortisol Test: This test involves taking cortisol levels at various times of the day and evaluating the body’s cortisol cycle. It can help determine if cortisol is produced in the right amounts, too much, or too little.

Blood Tests: Blood tests may include cortisol, DHEA (a hormone secreted by adrenal glands), and other tests that check adrenal function. These tests can give information on how well the adrenals are working.

ACTH Stimulation Test: While most often employed in the identification of Addison’s disease, this test can on occasion be used to evaluate adrenal function by measuring the adrenal glands’ reaction to ACTH stimulation.

Importance of Consulting a Healthcare Professional: Adrenal fatigue remains a contentious issue and it is recommended to seek medical advice for Managing and Recovering from Adrenal Fatigue.

Adrenal fatigue requires holistic management that entails a change of lifestyle and diet as well as stress reduction strategies. Because adrenal fatigue is the result of stress and unhealthy living, it also takes time to recover from adrenal fatigue.

Importance of Stress Reduction Techniques

Stress management is important in adrenal healing. Practices like meditation, mindfulness, deep breathing exercises, and yoga can assist in regulating the nervous system and relieving the pressure on the adrenal glands. Practicing relaxation techniques daily assists in the regulation of cortisol levels and thus promotes healthy hormonal balance. Other ways of decreasing stress may include going for a walk, engaging in hobbies, and interacting with people who will encourage one.

Diet Changes

Adrenal function is enhanced by taking nutrient-dense foods that are balanced. This involves:

Avoiding Caffeine: Caffeine triggers the adrenal glands to release cortisol into the bloodstream. Cutting down on caffeine can also help to avoid the overworking of the adrenals and experience more balanced energy during the day.

Eating Nutrient-Rich Foods: The incorporation of vegetables, fruits, lean proteins, and healthy fats as whole foods assists in the stabilization of blood sugar in addition to delivering the vitamins and minerals required for the adrenal glands. Vitamin C-containing foods, B vitamins, magnesium, and ashwagandha are the nutrients that help in the recovery of adrenal health.

Supplements and Vitamins for Adrenal Support

Specific supplements can be useful for the adrenal glands’ nourishment and support. Common supplements for adrenal fatigue include:

Vitamin C and B Vitamins: These vitamins are useful in the adrenal glands and hormone secretion. They assist the body to deal with stress and increase energy levels.

Magnesium: This mineral plays a role in the regulation of the nervous system, sleep, and the body’s response to stress.

Adaptogens: Some of these herbs include ashwagandha, rhodiola, and holy basil which can assist in controlling cortisol levels and enhancing the body’s ability to cope with stress.

Exercise Recommendations for Adrenal Fatigue Recovery

Though physical activity is good for health, vigorous exercise puts extra pressure on the adrenal glands. If the person is in the process of recovering from adrenal fatigue, then it is advised that they take up low-impact activities such as walking, yoga, tai chi or even stretching. These activities assist in increasing blood flow, decreasing stress, and increasing the general health of an individual without overworking the adrenal glands.

The Role of Sleep in Healing Adrenal Fatigue

The adrenal glands need time to recuperate, and this is only possible when one is well-rested. The body’s natural cortisol rhythm can be regulated by going to bed and waking up at the same time every day to establish a sleep routine. The implementation of a sleep schedule, which entails avoiding the use of electronic devices, low lighting, and relaxation exercises before going to bed, aids in enhancing the quality of sleep and assisting with the healing of the adrenal glands.

If adrenal fatigue is not treated, it may result in other severe health complications in the long run. This is especially so because persistent stress and sustained adrenal dysfunctions can impact multiple systems in the body.

Potential for Developing Chronic Fatigue Syndrome or Autoimmune Conditions: Adrenal fatigue if left untreated can lead to the development of chronic fatigue syndrome a condition that is characterized by severe and unexplained fatigue. The prolonged stress response can also suppress the immune system, thus making the body vulnerable to autoimmune diseases that occur when the immune system targets the body’s healthy tissues [2].

Effects on Long-term Hormonal Balance: It can also affect sex hormones such as estrogen, progesterone, and testosterone among women and men, respectively. It can cause hormonal imbalance that leads to irregular menstrual periods, infertility, or worsen PCOS and endometriosis. Also, long-term adrenal stress impacts hormonal balance and, therefore, thyroid hormones, which may result in hypothyroidism or other thyroid diseases.

Importance of Early Detection and Intervention: It is imperative to identify adrenal fatigue in the earliest stages and take the necessary measures to avoid adverse effects on health. The solutions to these problems include treating the underlying causes of adrenal dysfunction, including stress, poor diet, and sleep deprivation. Adoption of lifestyle changes, stress management, and nutrition can help reduce symptoms and avoid the worsening of other conditions.

FAQs

Can Adrenal Fatigue Cause Changes In Skin And Hair Health In Females?
Yes, adrenal fatigue can affect skin and hair. When the adrenal glands are fatigued, stress and hormonal changes may cause skin problems such as dryness, sensitivity, acne, and slow healing. Hair may become rough and some women may develop thinning of hair or even loss of hair. These changes occur because stress makes the body shift resources from other unimportant activities such as skin and hair growth.
Is It Possible For Adrenal Fatigue To Affect Fertility In Women?
Adrenal fatigue affects fertility because it affects the hormonal system. The adrenal glands also secrete sex hormones such as estrogen and progesterone among others. In cases where the adrenals are overactive, they are capable of interfering with the hormonal balance that is required in the process of ovulation and menstrual cycles. This can result in several conditions such as irregular menstrual cycles, anovulation, or luteal phase defects that can hinder conception.
Can Adrenal Fatigue Cause Cravings For Caffeine Or Alcohol?
Yes, women with adrenal fatigue may crave stimulants such as caffeine or depressants such as alcohol. These cravings happen because the body is looking for a way to increase energy levels or to help cope with stress. Caffeine stimulates the release of cortisol in the short-term giving the body a boost in energy. However, this can put pressure on the adrenal glands in the long run as they will be producing hormones throughout. Likewise, alcohol may be used to ‘‘relax” but it affects the quality of sleep and worsens adrenal fatigue.
How Does Adrenal Fatigue Affect The Body's Response To Exercise In Females?
Some women with adrenal fatigue may experience a decrease in the level of exercise they can handle. Strenuous or protracted exercise can be more draining than invigorating, thus; it takes longer time to regain strength and one may feel drained after exercises. This happens because the body is already stressed and when one engages in rigorous exercises, the adrenals are overworked and release more stress hormones than they should. Thus, simple walking gentle yoga, or any other exercise that does not raise cortisol levels much is more appropriate until adrenal function is enhanced.

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